2-Chloro-5-nitropyrimidine CAS:10320-42-0

1. 2-Chloro-5-nitropyrimidine is a fine chemical with key value in the fields of medicine and chemical industry. Its CAS number is 10320-42-0, its molecular formula is C4H2ClN3O2, and its molecular weight is 159.53. From the appearance, it appears as a yellow crystalline powder with a melting point of about 109°C. The product is slightly soluble in water and has a certain solubility in some organic solvents such as dichloromethane and N,N-dimethylformamide. It has good stability and is easy to store and transport.

2. In the field of organic synthesis, 2-chloro-5-nitropyrimidine is an extremely important intermediate. In pharmaceutical research and development, with its unique chemical structure, it can participate in the construction of a variety of drug molecules, such as antibacterial and antiviral drugs, and plays a key role in conquering various diseases; in pesticide synthesis, it can be used to prepare new and efficient pesticides to help prevent and control agricultural pests and diseases.

3. With a high purity (GC) of ≥98% and stable quality, this product can meet the stringent requirements of various scientific research experiments and industrial production, providing a solid guarantee for the innovative development of related fields.

product details

ZhonghanProduct Overview

2-Chloro-5-nitropyrimidine is an organic compound with important application value in organic synthesis, medicine and pesticides. Its unique structure and chemical properties enable it to play a key role in multiple industries.

ZhonghanStructural formula

Molecular formula	C4H2ClN3O2
Molecular weight	159.53
Density	1.600±0.06 g/cm3 (Predicted)
Storage condition	-20°C
Acidity coefficient (pKa)	-4.60±0.22 (Predicted)
Melting point	105-110 °C
Boiling point	345.4±15.0 °C (Predicted)
Form	Powder crystal
Color	Light orange to yellow to green

ZhonghanPhysical properties

1. Appearance: Usually yellow to off-yellow crystalline powder with a relatively regular crystal shape, which is easy to identify and handle.

2. Melting point: about 109℃. Melting point is one of the important indicators for identifying the purity of the product. During the production and quality control process, the purity and quality stability of the product can be determined by melting point determination.

3. Solubility: Slightly soluble in water, soluble in some organic solvents such as dichloromethane, N,N-dimethylformamide (DMF), acetonitrile, etc. This solubility characteristic determines its application in different chemical reaction systems, and the appropriate solvent can be selected for the synthesis reaction according to the reaction requirements.

4. Stability: It has good chemical stability under normal temperature, dry and light-proof conditions. However, in a strong alkaline or strong acidic enviroment, or under high temperature conditions, chemical reactions may occur, resulting in structural changes. Therefore, it is necessary to pay attention to the control of environmental conditions during storage and use.

ZhonghanApplication Areas

1. Pharmaceutical field: As an important pharmaceutical intermediate, 2-chloro-5-nitropyrimidine has a wide range of applications in drug research and development. The chlorine atom and nitro group in its molecular structure have high reactivity and can react with other compounds containing active groups through nucleophilic substitution, coupling and other reactions to construct drug molecules with specific biological activity. For example, it can be used to synthesize antibacterial drugs, antiviral drugs, anti-tumor drugs, etc., and contribute to human health.

2. Pesticide field: This compound also plays an important role in pesticide synthesis. It can be used to prepare new pesticide products such as insecticides, fungicides and herbicides. By modifying and optimizing its structure, it can give the pesticide molecule better biological activity and selectivity, improve the control effect of pesticides, and reduce the impact on the environment and non-target organisms.

3. Organic synthesis: 2-Chloro-5-nitropyrimidine is an important intermediate in organic synthesis and can be used to synthesize various nitrogen-containing heterocyclic compounds, functional materials, etc. Its unique structure and reactivity provide organic synthetic chemists with rich synthetic possibilities and help develop new organic compounds and materials.