5-BROMOPYRAZOLO[1,5-A]PYRIMIDINE CAS:1159981-95-9

5-Bromopyrazolo[1,5-A]pyrimidine is a key fine chemical in the field of organic synthesis and pharmaceutical research and development. Its CAS number is 500774-22-3, molecular formula C6H4BrN3, and molecular weight is 210.03. In appearance, it is a white to light yellow crystalline powder with stable properties and easy storage and transportation. It is slightly soluble in water and has good solubility in organic solvents such as dichloromethane and N,N-dimethylformamide, and can adapt to a variety of reaction systems.

In organic synthesis, it is an important intermediate for building complex molecular structures and can participate in a variety of reactions such as nucleophilic substitution and coupling. In the pharmaceutical field, it is often used to synthesize anticancer and antiviral drugs, playing a key role in conquering major diseases. With a high purity of ≥98% (HPLC), it can meet the stringent requirements of scientific research experiments and industrial production, providing a solid guarantee for the innovative development of related fields.

product details

ZhonghanProduct Overview

5-Bromopyrazolo[1,5-A]pyrimidine is an organic compound with important application value in organic synthesis, pharmaceutical research and development, and materials science. Its unique structure and active reaction properties provide key support for innovative development in many fields.

ZhonghanStructural formula

Molecular formula	C6H4BrN3
Molecular weight	198.02
Density	1.89±0.1 g/cm3 (Predicted)
Storage conditions	under inert gas (nitrogen or Argon) at 2-8°C
Acidity coefficient (pKa)	-0.50±0.30 (Predicted)

ZhonghanPhysical properties

1. Appearance: It is a white to light yellow crystalline powder under normal conditions. Its color and shape are stable, which facilitates quality control and identification during production, storage and transportation.
2. Melting point: [The specific melting point value needs to be accurately determined through professional experiments. Melting point is one of the important indicators for identifying product purity and is of key significance in the synthesis and purification process].

3. Solubility: Slightly soluble in water, it has good solubility in organic solvents such as dichloromethane, chloroform, N,N-dimethylformamide (DMF), acetonitrile, etc. This solubility feature enables it to be flexibly used in different organic reaction systems. The appropriate solvent can be selected according to the reaction requirements to promote the smooth progress of the reaction.

4. Stability: It has good chemical stability under the conditions of room temperature, dryness and light avoidance. However, due to the active bromine atoms in its molecular structure, chemical reactions may occur under certain conditions such as strong acid and alkali, high temperature or strong oxidants, resulting in structural changes. Therefore, during storage and use, environmental conditions need to be strictly controlled to avoid contact with incompatible substances.

ZhonghanApplication Areas

1. Pharmaceutical field: As an important pharmaceutical intermediate, it plays a core role in the research and development of new drugs. Its unique chemical structure and reactivity enable it to participate in the construction process of a variety of biologically active drug molecules. By reacting with other groups with specific pharmacological activities, a series of drugs with potential therapeutic value can be synthesized, such as anticancer drugs, antiviral drugs, antibacterial drugs, etc. For example, in the research and development of anticancer drugs, it can be used as a key structural unit to bind to specific targets of cancer cells, thereby effectively inhibiting the growth and proliferation of cancer cells; in the research of antiviral drugs, by modifying and transforming its structure, new drugs that have inhibitory effects on specific viruses can be synthesized, providing new means for the treatment of viral infectious diseases.

2. Materials Science: It has great potential in the synthesis of functional materials. Because its molecular structure contains conjugated systems and active bromine atoms, it can be used to prepare organic materials with special optical and electrical properties. For example, in the research and development of organic light-emitting diode (OLED) materials, introducing it into the molecular structure of the light-emitting material can adjust the material's emission wavelength and efficiency and improve the performance of OLED devices; in the research of organic semiconductor materials, it can also be used as an important structural unit to improve the material's charge transfer performance and provide support for the development of high-performance organic semiconductor devices.

3. Organic synthesis: It is an important tool in the hands of organic synthetic chemists and can be used to construct various complex organic molecular structures. Through its active bromine atom, it can carry out a variety of organic chemical reactions such as nucleophilic substitution and coupling, providing rich possibilities for the synthesis of organic compounds with specific structures and functions. It has a wide range of applications in the fields of total synthesis of natural products and synthesis of new organic catalysts. For example, in the total synthesis of natural products, 5-bromopyrazolo[1,5-A]pyrimidine can be used as an intermediate through a series of chemical reactions to construct natural product molecules with complex structures, providing a material basis for studying the biological activity and mechanism of action of natural products.