5-Chloropyrazolo[1,5-a]pyriMidine-3-carbonitrile CAS:1224288-92-9

1. 5-Chloropyrazolo[1,5-A]pyrimidine-3-carbonitrile is a fine chemical with important value in the field of organic synthesis and pharmaceutical chemicals. The unique combination of chlorine atoms, pyrazole rings, pyrimidine rings and methyl hydrogen groups in its molecular structure endows the product with special chemical activity and reaction selectivity;

2. In terms of appearance, it often appears as a white to off-white crystalline powder with high purity and good stability. In organic synthesis reactions, 5-chloropyrazolo[1,5-A]pyrimidine-3-carbonitrile, as a key intermediate, can participate in various types of reactions, such as nucleophilic substitution, coupling reaction, etc., providing a strong foundation for the construction of complex organic molecular structures;

3. In the pharmaceutical field, this product can be used as an important structural unit for the research and development of drugs with potential biological activity, such as anticancer drugs, antiviral drugs, etc. The active sites in its structure can specifically bind to targets in the body, thereby achieving therapeutic effects on the disease. At the same time, in the research and development of pesticides, 5-chloropyrazole [1,5-A] pyrimidine-3-carbonitrile has also shown good application prospects. It can be used to synthesize new, efficient, and low-toxic pesticide products to help control pests and diseases in agricultural production.

product details

ZhonghanProduct Overview

5-Chloropyrazolo[1,5-A]pyrimidine-3-carbonitrile is a fine organic compound with important application value in organic synthesis, medicine and pesticides.

ZhonghanStructural formula

Molecular formula	C7H3ClN4
Molecular weight	178.58
Boiling point	278.95°C (rough estimate)
Density	1.56±0.1 g/cm3 (Predicted)
Storage conditions	under inert gas (nitrogen or Argon) at 2-8°C
Acidity coefficient (pKa)	-3.08±0.40 (Predicted)
Melting point	138-142℃ (isopropanol)

ZhonghanPhysical properties

1. Appearance: Usually white to off-white crystalline powder with a relatively regular crystal shape.

2. Melting point: The melting point is relatively stable and is one of the important indicators for identifying the purity of the product, 180℃-190℃.

3. Solubility: Slightly soluble in water, with good solubility in some organic solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), but poor solubility in common low-grade organic solvents such as n-hexane and petroleum ether.

4. Stability: Under normal temperature, dry and light-proof conditions, the compound has good chemical stability, but under extreme conditions such as strong acid, alkali, high temperature, etc., chemical reactions may occur, resulting in structural changes.

ZhonghanApplication Areas

1. Pharmaceutical field: As an important pharmaceutical intermediate, 5-chloropyrazole [1,5-A] pyrimidine-3-carbonitrile plays a key role in drug research and development. Its unique molecular structure and active sites enable it to participate in the construction of a variety of drug molecules. For example, by modifying its structure and functionalizing it, new drugs with anti-tumor, antiviral, antibacterial and other biological activities can be developed, contributing to human health.

2. Pesticide field: In pesticide synthesis, this compound also has important application value. It can be introduced into pesticide molecules as a structural unit to give pesticide molecules specific biological activities, such as insecticide, fungicide, weed control and other properties, so as to develop new high-efficiency, low-toxic, environmentally friendly pesticide products to meet the needs of modern agricultural production teams for pesticides.

Materials Science: With the continuous development of materials science, 5-chloropyrazolo[1,5-A]pyrimidine-3-carbonitrile has also shown potential application prospects in the synthesis of some functional organic materials. For example, it can be used to prepare organic materials with special optical and electrical properties, providing new raw materials and ideas for the innovative development of materials science.